Cart
sales@molnova.com
SMIFH2
CAS No. 340316-62-3
SMIFH2( —— )
Catalog No. M27714 CAS No. 340316-62-3
SMIFH2 is formin homology 2 (FH2) domains inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
|
| 2MG | 38 | In Stock |
|
| 5MG | 61 | In Stock |
|
| 10MG | 92 | In Stock |
|
| 25MG | 188 | In Stock |
|
| 50MG | 367 | In Stock |
|
| 100MG | 546 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1070 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSMIFH2
-
NoteResearch use only, not for human use.
-
Brief DescriptionSMIFH2 is formin homology 2 (FH2) domains inhibitor.
-
DescriptionSMIFH2 is formin homology 2 (FH2) domains inhibitor.
-
In VitroSMIFH2 (25 uM; 1-16 hours) induces dynamic cytoskeletal remodelling in U2OS cells. SMIFH2 (25 μM) reduces p300, mDia2 and p53 levels in a proteasome-independent manner.SMIFH2 reduces expression and activity of p53 through a post-transcriptional, proteasome-independent mechanism that influences remodelling of the cytoskeleton. Western Blot Analysis Cell Line:293T, A375, U2OS, and MDA-MB-231 cells Concentration:25 μM Incubation Time:5 hours for 293T, U2OS, MDA-MB-231 cells; 2.5 hours for A375 cells Result:Downregulated mDia2, p53 and p300 protein levels.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptormGluR5
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number340316-62-3
-
Formula Weight377.21
-
Molecular FormulaC15H9BrN2O3S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (331.38 mM)
-
SMILESBrc1cccc(c1)N1C(=S)NC(=O)\C(=C/c2ccco2)C1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Keck TM, et al. A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats. Addict Biol.
molnova catalog
related products
-
KRM-III
KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell proliferation, with an IC50 of approximately 5 μM.
-
Peptide YY (3-36) (c...
Peptide YY (3-36) (canine, mouse, porcine, rat)
-
Argireline
Argireline (Acetyl hexapeptide-3) is composed of chains of amino acids known as peptides. Argireline significantly inhibits Ca2+ dependent neurotransmitter release (acetylcholine) at the neuromuscular junction.
