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MK-4827 Racemate

CAS No. 1038915-75-1

MK-4827 Racemate( Niraparib Racemate | 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide )

Catalog No. M27657 CAS No. 1038915-75-1

MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 115 In Stock
2MG 60 In Stock
5MG 85 In Stock
10MG 148 In Stock
25MG 282 In Stock
50MG 482 In Stock
100MG 649 In Stock
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Biological Information

  • Product Name
    MK-4827 Racemate
  • Note
    Research use only, not for human use.
  • Brief Description
    MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
  • Description
    MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Niraparib Racemate | 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1038915-75-1
  • Formula Weight
    320.396
  • Molecular Formula
    C19H20N4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C1CCCNC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.
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