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MK-4827 Racemate

CAS No. 1038915-75-1

MK-4827 Racemate( Niraparib Racemate | 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide )

Catalog No. M27657 CAS No. 1038915-75-1

MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 115 In Stock
2MG 60 In Stock
5MG 85 In Stock
10MG 148 In Stock
25MG 282 In Stock
50MG 482 In Stock
100MG 649 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    MK-4827 Racemate
  • Note
    Research use only, not for human use.
  • Brief Description
    MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
  • Description
    MK-4827 Racemate is a selective PARP1 and PARP2 inhibitor with IC50s of 3.8 nM and 2.1 nM, respectively, over 330-fold selectivity for PARP3, V-PARP and Tank1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Niraparib Racemate | 2-(4-piperidin-3-ylphenyl)indazole-7-carboxamide
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    PARP
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1038915-75-1
  • Formula Weight
    320.396
  • Molecular Formula
    C19H20N4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C1CCCNC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.
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