A 77636 hydrochloride

CAS No. 145307-34-2

A 77636 hydrochloride( A77636 hydrochloride )

Catalog No. M27461 CAS No. 145307-34-2

A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 217 In Stock
10MG 316 In Stock
25MG 533 In Stock
50MG 734 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    A 77636 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).
  • Description
    A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A-77636 hydrochloride shows antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor.(In Vivo):A-77636 (0.1-1 mg/kg) exerts a suppressant effect on food intake in male hooded rat, due principally to a reduction in meal size and duration.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male hooded ratDosage:0.1, 0.3 and 1.0 mg/kg Administration:S.c.Result:Exerted a suppressant effect on food intake, due principally to a reduction in meal size and duration.
  • Synonyms
    A77636 hydrochloride
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    Free radical scavengers|Platelet aggregation
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    145307-34-2
  • Formula Weight
    365.89
  • Molecular Formula
    C20H28ClNO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N)[C@@H]1O[C@H]([C@@]23CC4CC(C2)CC(C3)C4)CC=5C1=CC=C(O)C5O.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zbidi H, et al. Olive tree wood phenolic compounds with human platelet antiaggregant properties. Blood Cells Mol Dis. 2009 May-Jun;42(3):279-85.
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