A 77636 hydrochloride
CAS No. 145307-34-2
A 77636 hydrochloride( A77636 hydrochloride )
Catalog No. M27461 CAS No. 145307-34-2
A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 217 | In Stock |
|
| 10MG | 316 | In Stock |
|
| 25MG | 533 | In Stock |
|
| 50MG | 734 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameA 77636 hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionA-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM).
-
DescriptionA-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist (pKi=7.40; Ki=39.8 nM). A-77636 hydrochloride shows antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor.(In Vivo):A-77636 (0.1-1 mg/kg) exerts a suppressant effect on food intake in male hooded rat, due principally to a reduction in meal size and duration.
-
In Vitro——
-
In VivoAnimal Model:Male hooded ratDosage:0.1, 0.3 and 1.0 mg/kg Administration:S.c.Result:Exerted a suppressant effect on food intake, due principally to a reduction in meal size and duration.
-
SynonymsA77636 hydrochloride
-
PathwayGPCR/G Protein
-
TargetDopamine Receptor
-
RecptorFree radical scavengers|Platelet aggregation
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number145307-34-2
-
Formula Weight365.89
-
Molecular FormulaC20H28ClNO3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC(N)[C@@H]1O[C@H]([C@@]23CC4CC(C2)CC(C3)C4)CC=5C1=CC=C(O)C5O.Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zbidi H, et al. Olive tree wood phenolic compounds with human platelet antiaggregant properties. Blood Cells Mol Dis. 2009 May-Jun;42(3):279-85.
molnova catalog
related products
-
Tavapadon
Tavapadon (PF 6649751, PF-06649751) is an orally available dopamine D1 receptor partial agonist for treatment of Parkinson's disease.
-
ABT-724
ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM).
-
Dehydroevodiamine
Dehydroevodiamine, a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities.
Cart
sales@molnova.com