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BRL 52537 hydrochloride
CAS No. 112282-24-3
BRL 52537 hydrochloride( —— )
Catalog No. M27458 CAS No. 112282-24-3
BRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 106 | In Stock |
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| 5MG | 156 | In Stock |
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| 10MG | 222 | In Stock |
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| 25MG | 413 | In Stock |
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| 50MG | 606 | In Stock |
|
| 100MG | 862 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBRL 52537 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionBRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury.
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DescriptionBRL 52537 hydrochloride is a selective and specific KOR agonist which has been implicated in neuroprotection from ischemic neuronal injury. It is used for research into potential treatments for stroke and heart attack as well as more general brain research.(In Vivo):In rats treated with BRL 52537 during ischemia and early reperfusion, infarct volume was significantly attenuated in cortex and in caudoputamen.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayEndocrinology/Hormones
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TargetOpioid Receptor
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RecptorRARγ
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Research Area——
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Indication——
Chemical Information
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CAS Number112282-24-3
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Formula Weight391.76
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Molecular FormulaC18H25Cl3N2O
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(Cc(cc1)cc(Cl)c1Cl)N1C(CN2CCCC2)CCCC1.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hughes NE, et al. Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3274-3277.
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