Navuridine

CAS No. 84472-85-5

Navuridine( AZdU | AzUrd | CS-87 | 3'-Azido-2',3'-dideoxyuridine | CS 87 | AZddU )

Catalog No. M27413 CAS No. 84472-85-5

Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 71 In Stock
5MG 65 In Stock
10MG 112 In Stock
25MG 235 In Stock
50MG 365 In Stock
100MG 551 In Stock
200MG Get Quote In Stock
500MG 1190 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Navuridine
  • Note
    Research use only, not for human use.
  • Brief Description
    Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.
  • Description
    Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.
  • In Vitro
    ——
  • In Vivo
    Pharmacokinetic Parameters of 3′-Azido-2′,3′-dideoxyuridine in male Sprague-Dawley rats. Animal Model:Adult male Sprague-Dawley rats (300-400 g)Dosage:25, 100 mg/kg Administration:Intravenous bolus injection or oral gavage (Pharmacokinetic Analysis)Result:The oral bioavailability estimates of 3′-Azido-2′,3′-dideoxyuridine at doses of 25 and 100 mg/kg averaged 53%.
  • Synonyms
    AZdU | AzUrd | CS-87 | 3'-Azido-2',3'-dideoxyuridine | CS 87 | AZddU
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    84472-85-5
  • Formula Weight
    253.218
  • Molecular Formula
    C9H11N5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (987.32 mM)
  • SMILES
    OC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])n1ccc(=O)[nH]c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fang Liu, et al. N-3-oxo-octanoyl-homoserine lactone-mediated priming of resistance to Pseudomonas syringae requires the salicylic acid signaling pathway in Arabidopsis thaliana. BMC Plant Biol. 2020 Jan 28;20(1):38.
molnova catalog
related products
  • Helichrysetin

    Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives (2-6) from the methanol extract of Boesenbergia pandurata rhizomes.

  • SAMT-247

    SAMT-247 potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells.

  • Dolutegravir interme...

    Dolutegravir intermediate-1 is a new synthetic Dolutegravir intermediate extracted from patent WO 2016125192 A2.