Navuridine
CAS No. 84472-85-5
Navuridine( AZdU | AzUrd | CS-87 | 3'-Azido-2',3'-dideoxyuridine | CS 87 | AZddU )
Catalog No. M27413 CAS No. 84472-85-5
Navuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 71 | In Stock |
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| 5MG | 65 | In Stock |
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| 10MG | 112 | In Stock |
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| 25MG | 235 | In Stock |
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| 50MG | 365 | In Stock |
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| 100MG | 551 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | 1190 | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNavuridine
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NoteResearch use only, not for human use.
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Brief DescriptionNavuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.
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DescriptionNavuridine is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.
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In Vitro——
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In VivoPharmacokinetic Parameters of 3′-Azido-2′,3′-dideoxyuridine in male Sprague-Dawley rats. Animal Model:Adult male Sprague-Dawley rats (300-400 g)Dosage:25, 100 mg/kg Administration:Intravenous bolus injection or oral gavage (Pharmacokinetic Analysis)Result:The oral bioavailability estimates of 3′-Azido-2′,3′-dideoxyuridine at doses of 25 and 100 mg/kg averaged 53%.
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SynonymsAZdU | AzUrd | CS-87 | 3'-Azido-2',3'-dideoxyuridine | CS 87 | AZddU
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PathwayMicrobiology/Virology
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TargetHIV
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number84472-85-5
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Formula Weight253.218
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Molecular FormulaC9H11N5O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (987.32 mM)
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SMILESOC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])n1ccc(=O)[nH]c1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Helichrysetin
Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent, it has cytotoxic effect on four selected cancer cell lines, A549, MCF-7, Ca Ski, and HT-29.Searching for anti-HIV-1 protease (PR) inhibitors of Thai medicinal plants led to the isolation of a new cyclohexenyl chalcone named panduratin C and chalcone derivatives (2-6) from the methanol extract of Boesenbergia pandurata rhizomes.
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SAMT-247
SAMT-247 potent HIV-1 nucleocapsid protein NCp7 inhibitor with EC50 of 0.6 uM with low cellular toxicity (TC50>100 uM) in cultured and primary cells.
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Dolutegravir interme...
Dolutegravir intermediate-1 is a new synthetic Dolutegravir intermediate extracted from patent WO 2016125192 A2.
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