I-XW-053

CAS No. 5496-35-5

I-XW-053( I XW 053 | IXW053 | 4-(4,5-Diphenyl-1H-iMidazol-2-yl)benzoic Acid )

Catalog No. M27211 CAS No. 5496-35-5

I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-NTD interface) with micromolar affinity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG 27 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    I-XW-053
  • Note
    Research use only, not for human use.
  • Brief Description
    I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-NTD interface) with micromolar affinity.
  • Description
    I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-NTD interface) with micromolar affinity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    I XW 053 | IXW053 | 4-(4,5-Diphenyl-1H-iMidazol-2-yl)benzoic Acid
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    Smoothened
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5496-35-5
  • Formula Weight
    340.382
  • Molecular Formula
    C22H16N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Manetti F, et al. Design, synthesis and biological characterization of a new class of osteogenic (1H)-quinolone derivatives. Eur J Med Chem. 2016;121:747-757.
molnova catalog
related products
  • CX 04328

    CX 04328 (LEDGIN-6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM.

  • YLC2-155

    YLC2-155 is a novel potent HIV-1 reverse transcriptase (RT) inhibitor that inhibits both polymerase (IC50=2.6 uM) and RNase H function (IC50=0.65 uM) of RT.

  • NBD-14107

    A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.