5-Methyltryptamine hydrochloride

Research use only, not for human use.

5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT.

5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.(In Vitro):5-Methyltryptamine stimulates breakdown of endogenous [3H]inositol-labeled phosphoinositides in membranes prepared from blowfly salivary gland homogenates. 5-Methyltryptamine, in the presence of 10 microM GTP gamma S, increased the rate of inositol trisphosphate formation by approximately 500% within 30 s.(In Vivo):5-Methyltryptamine contracts trachea with lower potency (-log EC50 < 5) than 5-HT (-log EC50 = 6.98). Guinea pig tracheal contraction to 5-HT and 5-Methyltryptamine is inhibited by 1-(1-naphthyl)piperazine (1-NP, 30 nM).

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2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochloride

Endocrinology/Hormones

5-HT Receptor

Cleavable

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1010-95-3

210.71

C11H15ClN2

>98% (HPLC)

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Cl.Cc1ccc2[nH]cc(CCN)c2c1

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(-20℃)

With Ice Pack

≥ 2 years