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Ro 20-1724
CAS No. 29925-17-5
Ro 20-1724( Ro20-1724 | Ro 20-1724 | Ro-20-1724 | 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone )
Catalog No. M27133 CAS No. 29925-17-5
Ro20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
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| 5MG | 38 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 122 | In Stock |
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| 50MG | 174 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameRo 20-1724
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NoteResearch use only, not for human use.
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Brief DescriptionRo20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.
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DescriptionRo20-1724 is a widely used inhibitor of cyclic nucleotide phosphodiesterase with IC50 of 2.0 μM and Ki of 3.1 μM.(In Vivo):RO-20-1724 was found to not only improve learning and memory in MWM and PA paradigms but also restore STZ induced elevation in cholinesterase activity. Further, RO-20-1724 significantly reduced malondialdehyde and nitrite levels, and restored the glutathione levels indicating attenuation of oxidative stress.
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In Vitro——
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In Vivo——
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SynonymsRo20-1724 | Ro 20-1724 | Ro-20-1724 | 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone
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PathwayAngiogenesis
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TargetPDE
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RecptorIL-8| NOD2
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Research Area——
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Indication——
Chemical Information
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CAS Number29925-17-5
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Formula Weight278.352
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Molecular FormulaC15H22N2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 50 mg/mL (179.63 mM)
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SMILESCCCCOc1cc(CC2CNC(=O)N2)ccc1OC
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Rickard DJ, et al. Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway. PLoS One. 2013;8(8):e69619. Published 2013 Aug 1.
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