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N-Biotinyl-6-aminohexanoic acid

CAS No. 72040-64-3

N-Biotinyl-6-aminohexanoic acid( N-(+)-Biotinyl-6-aminohexanoic acid )

Catalog No. M27092 CAS No. 72040-64-3

N-Biotinyl-6-aminohexanoic acid can be used to perform N-terminal biotinylation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    N-Biotinyl-6-aminohexanoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    N-Biotinyl-6-aminohexanoic acid can be used to perform N-terminal biotinylation.
  • Description
    N-Biotinyl-6-aminohexanoic acid can be used to perform N-terminal biotinylation.(In Vitro):The SERS (surface-enhanced Raman scattering) of cyclohexyl isocyanide that silver nanoparticles modified with N-Biotinyl-6-aminohexanoic acid and cyclohexyl isocyanide can be anchored on a separate biotinylated substrate via the avidin-biotin interaction.Synthesis of p-nitrophenyl N-acetyllactosaminide with β-D-galactosidase, chemical reduction of the p-nitrophenyl group, and sialylation with sialyltransferase. The p-aminophenyl glycosides are successfully biotin-labeled through the coupling with N-Biotinyl-6-aminohexanoic acid to afford biotinylated oligosaccharides with an aminohexanosyl group and phenyl group as the spacers between the biotin and glycan. The biotin-labeled sugars were shown to be useful for immobilization and assay of the carbohydrate-lectin interactions by an optical biosensor based on surface plasmon resonance.
  • In Vitro
    Synthesis of p-nitrophenyl N-acetyllactosaminide with β-D-galactosidase, chemical reduction of the p-nitrophenyl group, and sialylation with sialyltransferase. The p-aminophenyl glycosides are then successfully biotin-labeled through the coupling with N-(+)-biotinyl-6- aminohexanoic acid to afford biotinylated oligosaccharides with an aminohexanosyl group and phenyl group as the spacers between the biotin and glycan.The SERS (surface-enhanced Raman scattering) of cyclohexyl isocyanide that silver nanoparticles modified with N-(+)-biotinyl-6-aminocaproic acid and cyclohexyl isocyanide can be anchored on a separate biotinylated substrate via the avidin-biotin interaction.
  • In Vivo
    ——
  • Synonyms
    N-(+)-Biotinyl-6-aminohexanoic acid
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    72040-64-3
  • Formula Weight
    357.47
  • Molecular Formula
    C16H27N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O)CCCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim KH, et al. 1-Carbomethoxy-β-Carboline,?Derived?from?Portulaca?oleracea?L.,?Ameliorates?LPS-Mediated?Inflammatory?Response?Associated?with?MAPK?Signaling?and?Nuclear?Translocation?of NF-κB.Molecules.?2019 Nov 7;24(22). pii: E4042.
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