Dihydrofluorescein diacetate

CAS No. 35340-49-9

Dihydrofluorescein diacetate( Diacetyldihydrofluorescein )

Catalog No. M27035 CAS No. 35340-49-9

Dihydrofluorescein diacetate is a fluorescent probe for measuring oxidative stress in cell-free systems and cellular models.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
50MG 27 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Dihydrofluorescein diacetate
  • Note
    Research use only, not for human use.
  • Brief Description
    Dihydrofluorescein diacetate is a fluorescent probe for measuring oxidative stress in cell-free systems and cellular models.
  • Description
    Dihydrofluorescein diacetate is a fluorescent probe for measuring oxidative stress in cell-free systems and cellular models.(In Vitro):Dihydrofluorescein diacetate is able to detect the presence of ROS in mitochondria. Dihydrofluorescein diacetate fluorescence sharply delineates filaments that correspond in all detail to TMRM-stained mitochondria. It enters mitochondria and reacts with ROS released in the matrix. Dihydrofluorescein diacetate may be a useful quantitative method to measure the oxidation potential of nanoparticle-treated cells. Dihydrofluorescein diacetate shows fluorescence of linear structures, consistent with mitochondria, in reoxygenated endothelium.
  • In Vitro
    Dihydrofluorescein diacetate may be a superior fluorescent probe for many cell-based studies. It is a better fluorescent probe for detecting intracellular oxidants because it is more reactive toward specific oxidizing species. Dihydrofluorescein diacetate demonstrates fluorescence of linear structures, consistent with mitochondria, in reoxygenated endothelium. Dihydrofluorescein diacetate is able to detect the presence of ROS in mitochondria. Dihydrofluorescein diacetate fluorescence was sharp and delineated thin filaments which corresponded in all details to TMRM-stained mitochondria. It enters mitochondria and reacts with ROS released in the matrix. Dihydrofluorescein diacetate could be an useful and quantitative method for measuring the oxidative potential of nanoparticle-treated cells.
  • In Vivo
    ——
  • Synonyms
    Diacetyldihydrofluorescein
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    S1P
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    35340-49-9
  • Formula Weight
    418.401
  • Molecular Formula
    C24H18O7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 106.5 mg/mL (254.54 )
  • SMILES
    CC(=O)Oc1ccc2C(c3ccc(OC(C)=O)cc3Oc2c1)c1ccccc1C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lee H, et al. 4-Deoxypyridoxine improves the viability of isolated pancreatic islets ex vivo. Islets. 2013 May-Jun;5(3):116-21.
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