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Speract TFA(76901-59-2(free base))
CAS No. ——
Speract TFA(76901-59-2(free base))( —— )
Catalog No. M22773 CAS No. ——
Speract TFA is a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.The stimulation of sperm with speract depolarizes the mitochondrion and increases the levels of NADH. Surprisingly, these responses are independent of external Ca(2+) and are due to the increase in intracellular pH (pHi) induced by speract.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 291 | In Stock |
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| 10MG | 487 | In Stock |
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| 25MG | 859 | In Stock |
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| 50MG | Get Quote | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSperact TFA(76901-59-2(free base))
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NoteResearch use only, not for human use.
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Brief DescriptionSperact TFA is a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.The stimulation of sperm with speract depolarizes the mitochondrion and increases the levels of NADH. Surprisingly, these responses are independent of external Ca(2+) and are due to the increase in intracellular pH (pHi) induced by speract.
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DescriptionSperact TFA is a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism.The stimulation of sperm with speract depolarizes the mitochondrion and increases the levels of NADH. Surprisingly, these responses are independent of external Ca(2+) and are due to the increase in intracellular pH (pHi) induced by speract. Speract, by regulating pHi, in addition to [Ca(2+)]i, may finely modulate mitochondrial metabolism to control motility and ensure that sperm reach the egg and fertilize it.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight891.92
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Molecular FormulaC38H57N11O14
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Purity>98% (HPLC)
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Solubility——
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SMILESOC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Darszon, Alberto, Garcia-Rincon, et al. Speract, a sea urchin egg peptide that regulates sperm motility, also stimulates sperm mitochondrial metabolism[J]. Biochimica Et Biophysica Acta Bioenergetics, 2016.
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