Cart
sales@molnova.com
(S,R,S)-AHPC TFA
CAS No. 1631137-51-3
(S,R,S)-AHPC TFA( VH032-NH2 TFA | VHL ligand 1 TFA )
Catalog No. M26954 CAS No. 1631137-51-3
(S,R,S)-AHPC TFA (VH032-NH2 TFA) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 369 | Get Quote |
|
| 10MG | 537 | Get Quote |
|
| 25MG | 876 | Get Quote |
|
| 50MG | 1161 | Get Quote |
|
| 100MG | 1593 | Get Quote |
|
| 500MG | 3195 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product Name(S,R,S)-AHPC TFA
-
NoteResearch use only, not for human use.
-
Brief Description(S,R,S)-AHPC TFA (VH032-NH2 TFA) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein.
-
Description(S,R,S)-AHPC TFA (VH032-NH2 TFA) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC TFA can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells.
-
In Vitro——
-
In Vivo——
-
SynonymsVH032-NH2 TFA | VHL ligand 1 TFA
-
PathwayOthers
-
TargetOther Targets
-
RecptorhERG| σ1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1631137-51-3
-
Formula Weight544.59
-
Molecular FormulaC24H31F3N4O5S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOC(=O)C(F)(F)F.Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](N)C(C)(C)C)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lan Y, et al. Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain. J Med Chem. 2014 Dec 26;57(24):10404-23.
molnova catalog
related products
-
Laminin (925-933)(TF...
Laminin (925-933) (TFA) is a peptide derived from residues 925-933 of the Laminin B1 chain that binds to the laminin receptor.
-
Achatin-1
Achatin-1
-
neo-gambogic acid
Neogambogic acid an active ingredient in garcinia can inhibit the growth of some solid tumors and result in an anticancer effect it may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.
