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(S,R,S)-AHPC-PEG2-NH2 hydrochloride
CAS No. 2097973-72-1
(S,R,S)-AHPC-PEG2-NH2 hydrochloride( VH032-PEG2-NH2 hydrochloride | VHL Ligand-Linker Conjugates 3 hydrochloride | E3 ligase Ligand-Linker Conjugates 6 )
Catalog No. M26952 CAS No. 2097973-72-1
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 25MG | 46 | In Stock |
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| 50MG | 70 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name(S,R,S)-AHPC-PEG2-NH2 hydrochloride
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NoteResearch use only, not for human use.
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Brief Description(S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
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Description(S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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SynonymsVH032-PEG2-NH2 hydrochloride | VHL Ligand-Linker Conjugates 3 hydrochloride | E3 ligase Ligand-Linker Conjugates 6
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PathwayOthers
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TargetOther Targets
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Recptor5-HT7
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Research Area——
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Indication——
Chemical Information
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CAS Number2097973-72-1
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Formula Weight612.18
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Molecular FormulaC28H42ClN5O6S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 150 mg/mL (245.03 mM)
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SMILESO=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Acetyl Dopamine Dime...
N-Acetyldopamine dimer-2 (compound 2) is a N-acetyldopamine dimer that can be isolated from the yellow powder form Periostracum Cicadae with antioxidant and anti-inflammatory activities. N-Acetyldopamine dimer-2 inhibits oxidized low-density lipoprotein (LDL) oxidation, ROS generation, NO production, and NF-κB activity.
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Isoeleutherin
Isoeleutherin is a naphthopyran derivative isolated from E. americana Merr. Et Heyne with anti-fungal, anti-viral, and anti-tumor activities. Isoeleutherin plays an important role in selective modulation of T helper cell-mediated immune responses.
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10-Undecen-1-ol
10-Undecen-1-ol is converted from ricinoleic acid. 10-Undecen-1-ol can be used as a comonomer for the introduction of functional groups.
