Cart
sales@molnova.com
Cbz-NH-PEG2-CH2COOH
CAS No. 165454-06-8
Cbz-NH-PEG2-CH2COOH( —— )
Catalog No. M26936 CAS No. 165454-06-8
Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 27 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCbz-NH-PEG2-CH2COOH
-
NoteResearch use only, not for human use.
-
Brief DescriptionCbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
DescriptionCbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorApoptosis| PDK4
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number165454-06-8
-
Formula Weight297.307
-
Molecular FormulaC14H19NO6
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESOC(=O)COCCOCCNC(=O)OCc1ccccc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lee D, et al. Discovery of Novel Pyruvate Dehydrogenase Kinase 4 Inhibitors for Potential Oral Treatment of Metabolic Diseases. J Med Chem. 2019 Jan 24;62(2):575-588.
molnova catalog
related products
-
P-SCN-Bn-DOTA
p-SCN-Bn-DOTA is a chelator that simultaneously binds radionuclides and links monoclonal antibodies.
-
AA92593
AA92593 has been used as a selective inhibitor of melanopsin.The involvement of melanopsin in the regulation of melatonin was also determined by using a specific inhibitor AA92593 and by inhibiting melanopsin-induced phospholipase C activation.
-
Chaetocin
Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively.
