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Protein Kinase C (530-558)
CAS No. 122613-29-0
Protein Kinase C (530-558)( ——— )
Catalog No. M40351 CAS No. 122613-29-0
Protein Kinase C (530-558), a peptide fragment of protein kinase C (PKC), is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
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Biological Information
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Product NameProtein Kinase C (530-558)
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NoteResearch use only, not for human use.
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Brief DescriptionProtein Kinase C (530-558), a peptide fragment of protein kinase C (PKC), is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption.
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DescriptionProtein Kinase C (530-558), a peptide fragment of protein kinase C (PKC), is a potent PKC activator. Protein Kinase C (530-558) significantly inhibits osteoclastic bone resorption.
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In VitroProtein Kinase C (530-558) (1 nM-1 μM, 24 h) causes a dose-responsive inhibition of bone resorption, which is accompanied by a rapid and distinctive change in osteoclast morphology.Cell Viability Assay Cell Line:Osteoclast cell Concentration:1 nM, 10 nM, 100 nM, 1 μM Incubation Time:24 h Result:Showed a dose-responsive, marked inhibition of bone resorption was observed between 10 nM and 1 μM. At 1 μM, resorption was inhibited by more thaln 87 %.
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In Vivo———
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Synonyms———
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PathwayOthers
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TargetOther Targets
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Recptor———
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Research Area———
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Indication———
Chemical Information
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CAS Number122613-29-0
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Formula Weight3354.7
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Molecular FormulaC148H220N34O51S2
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Purity>98% (HPLC)
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Solubility———
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SMILES———
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Moonga BS, et al. Effects of peptide fragments of protein kinase C on isolated rat osteoclasts. Exp Physiol. 1998 Nov;83(6):717-25.?
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