Cbz-NH-PEG1-CH2COOH

CAS No. 1260092-43-0

Cbz-NH-PEG1-CH2COOH( —— )

Catalog No. M26934 CAS No. 1260092-43-0

Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
100MG 33 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Cbz-NH-PEG1-CH2COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    Cbz-NH-PEG1-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    anandamide cellular uptake| CB1| Human Endogenous Metabolite| TRPV1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1260092-43-0
  • Formula Weight
    253.254
  • Molecular Formula
    C12H15NO5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (394.87 mM)
  • SMILES
    OC(=O)COCCNC(=O)OCc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65(9):1473-81.
molnova catalog
related products
  • N-Methylpyrrolidone

    N-Methylpyrrolidone (1-Methyl-2-pyrrolidinone) is a five-membered cyclic amide. N-Methylpyrrolidone is a widely used industrial organic polar solvent in the manufacture of adhesives, paints, fuels, and pharmaceuticals.

  • Dextrothyroxine

    Dextrothyroxine could lower cholesterol and also increases hepatic lipase which in turn improves utilization of triglycerides, leading to improve apolipoprotein E cholesterol particles.

  • Cortistatin-29 (rat)

    Cortistatin-29 is a neuropeptide. Cortistatin-29 alleviates neuropathic pain. Cortistatin-29 binds all somatostatin (SS) receptor subtypes with high affinity and shows IC50 values of 2.8 nM, 7.1 nM, 0.2 nM, 3.0 nM, 13.7 nM for SSTR1, SSTR2, SSTR3, SSTR4, SSTR5, respectively. Cortistatin-29 shows anti-fibrotic effects.