Biotin-PEG6-Boc( Biotin-PEG6-t-butyl ester )

Catalog No. M26910 CAS No. 1352814-07-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Biotin-PEG6-Boc
Note

Research use only, not for human use.
Brief Description

Biotin-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Description

Biotin-PEG6-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

Biotin-PEG6-t-butyl ester
Pathway

Others
Target

Other Targets
Recptor

GPR40
Research Area

——
Indication

——

CAS Number

1352814-07-3
Formula Weight

635.81
Molecular Formula

C29H53N3O10S
Purity

>98% (HPLC)
Solubility

——
SMILES

[H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCC(=O)OC(C)(C)C)[C@@]1([H])NC(=O)N2
Chemical Name

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1.Houze JB, et al. AMG 837: a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1267-70.

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