Biotin-C5-amino-C5-amino
CAS No. 89889-51-0
Biotin-C5-amino-C5-amino( —— )
Catalog No. M26900 CAS No. 89889-51-0
Biotin-C5-amino-C5-amino is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBiotin-C5-amino-C5-amino
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NoteResearch use only, not for human use.
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Brief DescriptionBiotin-C5-amino-C5-amino is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
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DescriptionBiotin-C5-amino-C5-amino is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAngiotensin-converting Enzyme (ACE)
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Research Area——
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Indication——
Chemical Information
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CAS Number89889-51-0
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Formula Weight470.63
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Molecular FormulaC22H38N4O5S
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Purity>98% (HPLC)
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Solubility——
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SMILES[H][C@]12CS[C@@H](CCCCC(=O)NCCCCCC(=O)NCCCCCC(O)=O)[C@@]1([H])NC(=O)N2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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PF-03814735
PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.
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E-3030
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