Tolycaine

Research use only, not for human use.

Tolycaine is a compound of local anesthetic.

Tolycaine is a compound of local anesthetic.

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Tolycaine (140, 150 mg/kg; i.p.; single) induces convulsions by modification of monoamines in rat brain. Animal Model:Male Wistar rats (190-230 g).Dosage:130, 140, 150, 165 mg/kg Administration:Intraperitoneal injection; single.Result:Produced clonic convulsions following ataxia and the loss of the righting reflex and the frequency of convulsions was dose-dependently intensified, as shown by shortening of the latency and prolongations of the duration and the sedation time.Produced a significant elevation of noradrenaline and 5-hydroxytryptamine levels in all brain regions in the convulsive state from the levels in the non-convulsive state when at 140 mg/kg.Led to rats took the opisthotonic position, gasped for breath, and died during the cdnvulsions when dosage more than 150 mg/kg.

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Others

Other Targets

Bacterial

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3686-58-6

278.352

C15H22N2O3

>98% (HPLC)

In Vitro:?DMSO : ≥ 100 mg/mL (359.26 mM)

CCN(CC)CC(=O)Nc1c(C)cccc1C(=O)OC

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(-20℃)

With Ice Pack

≥ 2 years