SBI-425( —— )

Catalog No. M26818 CAS No. 1451272-71-1

SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	75	In Stock
5MG	68	In Stock
10MG	113	In Stock
25MG	182	In Stock
50MG	260	In Stock
100MG	386	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SBI-425
Note

Research use only, not for human use.
Brief Description

SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP).
Description

SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival without a detectable change in the bone.
In Vitro

SBI-425 treatment suppresses Foxp3 expression in CD4+ and CD8+ T cells in splenocytes from CLP-injured mice.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

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Chemical Information

CAS Number

1451272-71-1
Formula Weight

341.77
Molecular Formula

C13H12ClN3O4S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 86.67 mg/mL (253.59 mM)
SMILES

COc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.A L Tarentino, et al. 2-Iminothiolane: a reagent for the introduction of sulphydryl groups into oligosaccharides derived from asparagine-linked glycans. Glycobiology. 1993 Jun;3(3):279-85.

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