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Glibornuride

CAS No. 26944-48-9

Glibornuride( —— )

Catalog No. M26696 CAS No. 26944-48-9

Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75). Glibornuride inhibits high affinity [3H]-glibenclamide binding with the potencies expected from their K+ channel activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 170 In Stock
5MG 155 In Stock
10MG 250 In Stock
25MG 432 In Stock
50MG 600 In Stock
100MG 830 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Glibornuride
  • Note
    Research use only, not for human use.
  • Brief Description
    Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75). Glibornuride inhibits high affinity [3H]-glibenclamide binding with the potencies expected from their K+ channel activity.
  • Description
    Glibornuride is a blocker of ATP-sensitive K+ channel(pKi: 5.75). Glibornuride inhibits high affinity [3H]-glibenclamide binding with the potencies expected from their K+ channel activity.(In Vivo):The diabetic group, given Glibornuride(5mg/kg), blood glucose, serum alkaline phosphatase activity, serum sialic acid, uric acid, potassium, and liver NEG levels decreased, but liver LPO, GSH, serum sodium levels, and body weight increased.
  • In Vitro
    ——
  • In Vivo
    Animal Model:6-6.5-month-old male Swiss Albino rats, weighing 150-200 g Dosage:5 mg/kg Administration:Given by gavage, daily for 28 days Result:Administration for 28 days caused an increase in body weights in the diabetic groups. Treatment for 28 days decreased the serum uric acid levels in diabetic rats.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    26944-48-9
  • Formula Weight
    366.48
  • Molecular Formula
    C18H26N2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (682.17 mM)
  • SMILES
    [H][C@@]12CC[C@@](C)([C@@H](O)[C@H]1NC(=O)NS(=O)(=O)c1ccc(C)cc1)C2(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cheng Y, et al. 4-Methoxyestradiol-induced oxidative injuries in human lung epithelial cells. Toxicol Appl Pharmacol. 2007 May 1;220(3):271-7.
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