Cart
sales@molnova.com
Ertugliflozin L-pyroglutamic acid
CAS No. 1210344-83-4
Ertugliflozin L-pyroglutamic acid( PF-04971729 L-pyroglutamic acid )
Catalog No. M26680 CAS No. 1210344-83-4
Ertugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 5MG | 37 | In Stock |
|
| 10MG | 52 | In Stock |
|
| 25MG | 78 | In Stock |
|
| 50MG | 90 | In Stock |
|
| 100MG | 133 | In Stock |
|
| 200MG | 194 | In Stock |
|
| 500MG | 333 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameErtugliflozin L-pyroglutamic acid
-
NoteResearch use only, not for human use.
-
Brief DescriptionErtugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM.
-
DescriptionErtugliflozin L-pyroglutamic acid is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.(In Vitro):Ertugliflozin L-pyroglutamic acid demonstrated >2000-fold selectivity for SGLT2 over SGLT.(In Vivo):The oral administration of Ertugliflozin L-pyroglutamic to rats acid showed concentration-dependent glucosuria.
-
In Vitro——
-
In Vivo——
-
SynonymsPF-04971729 L-pyroglutamic acid
-
PathwayOthers
-
TargetOther Targets
-
RecptorCaspase-3
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1210344-83-4
-
Formula Weight566
-
Molecular FormulaC27H32ClNO10
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 125 mg/mL (220.85 mM)
-
SMILESOC(=O)[C@@H]1CCC(=O)N1.CCOc1ccc(Cc2cc(ccc2Cl)[C@]23OC[C@](CO)(O2)[C@@H](O)[C@H](O)[C@H]3O)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kravchenko DV, et al. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. J Med Chem. 2005 Jun 2;48(11):3680-3.
molnova catalog
related products
-
p-cumylphenol
p-cumylphenol can treat R enal Tubular Cyst Formation in Newborn Rats.
-
Lactupicrin
Lactupicrin is a characteristic bitter sesquiterpene lactone that can relieve pain. Lactupicrin exhibits atheroprotective effect.
-
α-Factor Mating Pher...
The alpha factor pheromone arrests yeast in the G1 phase of their cell cycle. Alpha Factor Mating Pheromone induces the expression of mating genes, changes in nuclear architecture, and polarzes growth toward the mating partner.
