Meglumine( 1-Deoxy-1-(methylamino)-D-glucitol | Iosulamide | N-Methyl-D-glucamine )

Catalog No. M15376 CAS No. 6284-40-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Meglumine
Note

Research use only, not for human use.
Brief Description

Meglumine is an amino sugar derived from sorbitol.
Description

Meglumine is an amino sugar derived from sorbitol. It is often used as an excipient in pharmaceuticals and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine and iodipamide meglumine.
In Vitro

Western Blot Analysis Cell Line:C2C12 mouse myoblasts Concentration:0, 10, 30, 100, 300 mM or 200 mM Incubation Time:60 min or 0, 10, 30, 60, 120 min Result:Increased the levels of SNARK protein in a dose-dependent manner after 60 min and reached a plateau at 30 minutes.
In Vivo

Animal Model:Sprague-Dawley ratDosage:25 or 50 mM Administration:p.o., dissolve in water Result:Reduced the isoprostane levels in rats.Animal Model:K6/ODC transgenic mice Dosage:37.5 mM Administration:p.o., dissolve in water Result:Reduced the number of skin tumors and inhibited tumor growth.Animal Model:KK.Cg-Ay/J mice Dosage:18 mM Administration:p.o., in drinking water Result:Performed better in a glucose tolerance test.Decreased their average fasting levels of glucose and triglyceride levels in both the liver and blood serum.
Synonyms

1-Deoxy-1-(methylamino)-D-glucitol | Iosulamide | N-Methyl-D-glucamine
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

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1.Navaei A, et al. Drug Dev Ind Pharm. 2014 Jun;40(6):701-10.

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