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Crolibulin
CAS No. 1000852-17-4
Crolibulin( EPC2407 )
Catalog No. M26657 CAS No. 1000852-17-4
Crolibulin is an inhibitor of small molecule tubulin polymerization.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 147 | Get Quote |
|
| 10MG | 267 | Get Quote |
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| 25MG | 441 | Get Quote |
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| 50MG | 655 | Get Quote |
|
| 100MG | 888 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCrolibulin
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NoteResearch use only, not for human use.
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Brief DescriptionCrolibulin is an inhibitor of small molecule tubulin polymerization.
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DescriptionCrolibulin is an inhibitor of small molecule tubulin polymerization.(In Vitro):Crolibulin shows significant cytotoxic activity against HT-29 cells, with an IC50 of 0.52 μM. Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage.
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In VitroCrolibulin shows significant cytotoxic activity against HT-29 cells, with an IC50 of 0.52 μM.Crolibulin is active against various experimental tumors and exhibit potent inhibition of mitosis at the G2/M stage.
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In Vivo——
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SynonymsEPC2407
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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Recptorlysosomal cysteine protease| Proton pump
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Research Area——
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Indication——
Chemical Information
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CAS Number1000852-17-4
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Formula Weight417.263
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Molecular FormulaC18H17BrN4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (299.57 mM)
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SMILESCOc1cc(cc(Br)c1OC)[C@H]1C(C#N)=C(N)Oc2c(N)c(N)ccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhao T, et al. Esomeprazole inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Invest New Drugs. 2021 Apr;39(2):337-347.
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