NSC639829
CAS No. 134742-19-1
NSC639829( NSC-639829 | NSC 639829 )
Catalog No. M11410 CAS No. 134742-19-1
A potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
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| 50MG | 1782 | Get Quote |
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| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNSC639829
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NoteResearch use only, not for human use.
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Brief DescriptionA potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines.
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DescriptionA potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization.
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In Vitro——
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In Vivo——
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SynonymsNSC-639829 | NSC 639829
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptorMicrotubule/Tubulin
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Research Area——
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Indication——
Chemical Information
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CAS Number134742-19-1
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Formula Weight470.327
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Molecular FormulaC21H20BrN5O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC(NC1=CC=C(OC2=NC=C(Br)C=N2)C(C)=C1)=O)C3=CC=CC=C3N(C)C
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Chemical NameN-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-(dimethylamino)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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SSE15206
SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance. Causes aberrant mitosis resulting in G2/M arrest due to incomplete spindle formation in cancer cells.
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Taccalonolide A
Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects,with cytotoxic and antimalarial activities.?Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis.
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Vincristine sulfate
Vincristine (sulfate) is an inhibitor of polymerization of microtubules by binding to tubulin with IC50?of 32 μM.
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