NSC639829

CAS No. 134742-19-1

NSC639829( NSC-639829 | NSC 639829 )

Catalog No. M11410 CAS No. 134742-19-1

A potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    NSC639829
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines.
  • Description
    A potent anticancer agent that demonstrates potent antitumor activity in vitro against several cancer cell lines as well as in vivo against several tumor models, effectively inhibits in vitro tubulin polymerization.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NSC-639829 | NSC 639829
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    Microtubule/Tubulin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    134742-19-1
  • Formula Weight
    470.327
  • Molecular Formula
    C21H20BrN5O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NC(NC1=CC=C(OC2=NC=C(Br)C=N2)C(C)=C1)=O)C3=CC=CC=C3N(C)C
  • Chemical Name
    N-((4-((5-bromopyrimidin-2-yl)oxy)-3-methylphenyl)carbamoyl)-2-(dimethylamino)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Abdel-Aziz W, et al. Invest New Drugs. 2003 Nov;21(4):421-8. 2. Jain A, et al. AAPS PharmSciTech. 2003 Oct 15;4(4):E52. 3. Balcer-Kubiczek EK, et al. Cancer Chemother Pharmacol. 2007 May;59(6):781-7. 4. Hallur G, et al. J Med Chem. 2006 Apr 6;49(7):2357-60.
molnova catalog
related products
  • SSE15206

    SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance. Causes aberrant mitosis resulting in G2/M arrest due to incomplete spindle formation in cancer cells.

  • Taccalonolide A

    Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects,with cytotoxic and antimalarial activities.?Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis.

  • Vincristine sulfate

    Vincristine (sulfate) is an inhibitor of polymerization of microtubules by binding to tubulin with IC50?of 32 μM.