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Home - Products - Membrane Transporter/Ion Channel - P2X Receptor - AZ10606120 dihydrochloride

AZ10606120 dihydrochloride

CAS No. 607378-18-7

AZ10606120 dihydrochloride( —— )

Catalog No. M26620 CAS No. 607378-18-7

AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 154 Get Quote
5MG 141 Get Quote
10MG 227 Get Quote
25MG 454 Get Quote
50MG 640 Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    AZ10606120 dihydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth.
  • Description
    AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth. AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM and it is little or no effect at other P2XR subtypes.
  • In Vitro
    ——
  • In Vivo
    Animal Model:LPS-induced anhedonia miceDosage:2 mg/kg Administration:i.p., pretreated at 30 min before LPS injection Result:Restored the decline in sucrose consumption, indicated by an sucrose preference test (SPT).
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    P2X Receptor
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    607378-18-7
  • Formula Weight
    495.49
  • Molecular Formula
    C25H36Cl2N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 8.33 mg/mL (16.81 mM)
  • SMILES
    Cl.Cl.OCCNCCNc1ccc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)cccc2n1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chung HK, et al. Plasma phospholipid arachidonic acid and lignoceric acid are associated with the risk of cardioembolic stroke. Nutr Res. 2015 Nov;35(11):1001-8.
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