5-Aminouridine

Research use only, not for human use.

5-Aminouridine modifies nucleobases and is incorporated into the target DNA. 5-Aminouridine inhibits the growth of tumors, viruses, and fungi.

5-Aminouridine modifies nucleobases and is incorporated into the target DNA. 5-Aminouridine inhibits the growth of tumors, viruses, and fungi.(In Vitro):5-Aminouridine inhibits the incorporation of carbamyl aspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma. 5-Aminouridine must exhibit a low potential to be oxidized by Os(bpy)33+. The modified nucleobase is inserted into the target DNA by direct synthesis using modified phosphoramidites.(In Vivo):5-Aminouridine inhibits the incorporation of carbamoylaspartate into pyrimidines in living rat RNA and DNA, and the incorporation of [32P]phosphate into phospholipids and RNA nucleotides in rat liver slices and liver cancers .

This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)33+. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites.

5-Aminouridine inhibits incorporation of carbamylaspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma.

4-Chloro-2-isopropyl-5-methylphenol(chlorothymol)

Cell Cycle/DNA Damage

Nucleoside Antimetabolite/Analog

GLP-1

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2149-76-0

259.22

C9H13N3O6

>98% (HPLC)

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O[C@H]1[C@@](O[C@H](CO)[C@H]1O)(N2C(=O)NC(=O)C(N)=C2)[H]

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(-20℃)

With Ice Pack

≥ 2 years