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4-Vinylphenol
CAS No. 2628-17-3
4-Vinylphenol( —— )
Catalog No. M26541 CAS No. 2628-17-3
4-Vinylphenol is the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine found in Hedyotis diffusa Willd. 4-Vinylphenol induces apoptosis in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 33 | In Stock |
|
| 500MG | 52 | In Stock |
|
| 1G | 83 | In Stock |
|
Biological Information
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Product Name4-Vinylphenol
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NoteResearch use only, not for human use.
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Brief Description4-Vinylphenol is the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine found in Hedyotis diffusa Willd. 4-Vinylphenol induces apoptosis in vivo.
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Description4-Vinylphenol is the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine found in Hedyotis diffusa Willd. 4-Vinylphenol induces apoptosis in vivo.(In Vitro):4-Vinylphenol (100 μg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis. 4-Vinylphenol (50, 100 μg/mL) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol (12.5-200 μg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 μg/mL. 4-Vinylphenol (0.15, 0.3 μg/mL) reduces sphere formation and vimentin expression on CSCs in breast cancer. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells.
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In Vitro4-Vinylphenol (12.5-200 μg/mL) significantly reduces cell viability in parental MDA-MB-231 cells, and the IC50 value is 109 μg/mL. 4-Vinylphenol (0.15 or 0.3 μg/mL; 3 days) reduces sphere?formation and vimentin expression on CSCs in breast cancer. 4-Vinylphenol (50, 100 μg/mL; 72 hours) significantly suppresses cell proliferation in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol significantly reduces ALDH1A1 expression by 50% in CSC-enriched MDA-MB-231 cells. 4-Vinylphenol (100 μg/mL) significantly increases the expressions of caspase 3, likely sensitizing CSC-enriched MDAMB-231 cells to apoptosis.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorHCV NS5A
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Research Area——
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Indication——
Chemical Information
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CAS Number2628-17-3
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Formula Weight120.151
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Molecular FormulaC8H8O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (832.29 mM)
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SMILESOc1ccc(C=C)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gao Y, et al. Coblopasvir and sofosbuvir for treatment of chronic hepatitis C virus infection in China: A single-arm, open-label, phase 3 trial. Liver Int. 2020;40(11):2685-2693.
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