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Zandelisib
CAS No. 1401436-95-0
Zandelisib( ME-401 | PWT-143 )
Catalog No. M26519 CAS No. 1401436-95-0
Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 225 | In Stock |
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| 5MG | 178 | In Stock |
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| 10MG | 278 | In Stock |
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| 25MG | 487 | In Stock |
|
| 50MG | 641 | In Stock |
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| 100MG | 882 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameZandelisib
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NoteResearch use only, not for human use.
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Brief DescriptionZandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.
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DescriptionZandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.(In Vitro):Zandelisib inhibits PI3Ks(p110α, p110β, p110γ and p110δ with IC50s of 4, 976 nM, 605 nM, 817 nM and 3.5 nM, respectivey).
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In Vitro——
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In Vivo——
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SynonymsME-401 | PWT-143
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number1401436-95-0
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Formula Weight576.697
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Molecular FormulaC31H38F2N8O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 33.33 mg/mL (57.80 mM)
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SMILESCN1CCC(CC1)c1ccccc1CC(C)(C)Nc1nc(nc(n1)-n1c(nc2ccccc12)C(F)F)N1CCOCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Llado V, et al. Minerval induces apoptosis in Jurkat and other cancer cells. J Cell Mol Med. 2010 Mar;14(3):659-70.
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