Telomerase-IN-2

CAS No. 1610878-54-0

Telomerase-IN-2( Telomerase inhibitor 2 )

Catalog No. M26478 CAS No. 1610878-54-0

Telomerase-IN-2 shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 446 In Stock
5MG 319 In Stock
10MG 468 In Stock
25MG 847 In Stock
50MG 1237 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Telomerase-IN-2
  • Note
    Research use only, not for human use.
  • Brief Description
    Telomerase-IN-2 shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 μM).
  • Description
    Telomerase-IN-2 shows potent inhibitory activity against telomerase by decreasing the expression of dyskerin (IC50: 0.89 μM).(In Vitro):Telomerase-IN-2 exhibits high activity against Hela, SMMC-7721, SGC-7901, U87 and HepG2 cell lines in the anticancer activity assay in vitro.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Telomerase inhibitor 2
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Telomerase
  • Recptor
    IRE1/XBP1s
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1610878-54-0
  • Formula Weight
    633.698
  • Molecular Formula
    C34H39N3O9
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (394.51 mM)
  • SMILES
    COc1cc(OC)c2c(c1)oc(-c1cc(OC)c(OC)c(OC)c1)c(OCCCCN1CCN(CC1)C(=O)c1ccncc1)c2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Grandjean JMD, et al. Pharmacologic IRE1/XBP1s activation confers targeted ER proteostasis reprogramming. Nat Chem Biol. 2020;16(10):1052-1061.
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