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TAS4464 hydrochloride
CAS No. 1848959-11-4
TAS4464 hydrochloride( —— )
Catalog No. M26476 CAS No. 1848959-11-4
TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 167 | In Stock |
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| 5MG | 140 | In Stock |
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| 10MG | 227 | In Stock |
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| 25MG | 455 | In Stock |
|
| 50MG | 737 | In Stock |
|
| 100MG | 1274 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTAS4464 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionTAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).
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DescriptionTAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetE1
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1848959-11-4
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Formula Weight542.97
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Molecular FormulaC21H24ClFN6O6S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (184.17 mM)
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SMILESCl.CCOc1cccc(F)c1C#Cc1cn([C@@H]2O[C@H](CNS(N)(=O)=O)[C@@H](O)[C@H]2O)c2ncnc(N)c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Li Q, Zhou W, Wang Y, Kou F, Lyu C, Wei H. Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide. Life Sci. 2020 Nov 15;261:118433.
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