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Sigma-1 receptor antagonist 2
CAS No. 1639220-15-7
Sigma-1 receptor antagonist 2( —— )
Catalog No. M26444 CAS No. 1639220-15-7
Sigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 107 | In Stock |
|
| 5MG | 98 | In Stock |
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| 10MG | 164 | In Stock |
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| 25MG | 276 | In Stock |
|
| 50MG | 384 | In Stock |
|
| 100MG | 520 | In Stock |
|
| 200MG | 697 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSigma-1 receptor antagonist 2
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NoteResearch use only, not for human use.
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Brief DescriptionSigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
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DescriptionSigma-1 receptor antagonist 2 is a more potent and selective antagonist of sigma 1 receptor (σ1 R, Ki = 3.88 nM) than σ2 receptor (Ki = 1288 nM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetSigma receptor
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RecptorAldose reductase
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Research Area——
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Indication——
Chemical Information
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CAS Number1639220-15-7
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Formula Weight375.9
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Molecular FormulaC20H26ClN3O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 86.67 mg/mL (230.57 mM)
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SMILESCOc1ccc(cc1)-c1nc(C)c(Cl)c(OCCCN2CCCCC2)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Carrington AL, et al. Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats. Diabetologia. 1991 Jun;34(6):397-401.
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