S1PR1 modulator 1( —— )

Catalog No. M26430 CAS No. 2328109-05-1

S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

S1PR1 modulator 1
Note

Research use only, not for human use.
Brief Description

S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
Description

S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.(In Vitro):S1PR1 modulator 1 shows >40- and >80-fold selectivity, over the other S1PR isoforms S1PR3 (pIC50, 6), S1PR2 and S1PR4 (pIC50s, <5).
In Vitro

S1PR1 modulator 1 (Compound 10a; (Z,Z)-10a) is selective at S1PR1 over S1PR3 (pIC50, 6), S1PR2 and S1PR4 (pIC50s, <5).
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Fungal| glucan synthase
Research Area

——
Indication

——

Chemical Information

CAS Number

2328109-05-1
Formula Weight

408.51
Molecular Formula

C23H24N2O3S
Purity

>98% (HPLC)
Solubility

——
SMILES

N(\CCC)=C\1/N(C(=O)\C(=C\C2=CC(C)=C(OC(C)=O)C=C2)\S1)C3=C(C)C=CC=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Miesel L, et al. Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and Pneumocystis Pneumonia. Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01992-20.

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