S1PR1 modulator 1

CAS No. 2328109-05-1

S1PR1 modulator 1( —— )

Catalog No. M26430 CAS No. 2328109-05-1

S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 131 In Stock
5MG 113 In Stock
10MG 164 In Stock
25MG 271 In Stock
50MG 392 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    S1PR1 modulator 1
  • Note
    Research use only, not for human use.
  • Brief Description
    S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.
  • Description
    S1PR1 modulator 1 is a selective inhibitor of S1PR1 with a pIC50 of 7.6.(In Vitro):S1PR1 modulator 1 shows >40- and >80-fold selectivity, over the other S1PR isoforms S1PR3 (pIC50, 6), S1PR2 and S1PR4 (pIC50s, <5).
  • In Vitro
    S1PR1 modulator 1 (Compound 10a; (Z,Z)-10a) is selective at S1PR1 over S1PR3 (pIC50, 6), S1PR2 and S1PR4 (pIC50s, <5).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Fungal| glucan synthase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2328109-05-1
  • Formula Weight
    408.51
  • Molecular Formula
    C23H24N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(\CCC)=C\1/N(C(=O)\C(=C\C2=CC(C)=C(OC(C)=O)C=C2)\S1)C3=C(C)C=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Miesel L, et al. Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and Pneumocystis Pneumonia. Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01992-20.
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