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CGP 35348

CAS No. 123690-79-9

CGP 35348( —— )

Catalog No. M27465 CAS No. 123690-79-9

CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CGP 35348
  • Note
    Research use only, not for human use.
  • Brief Description
    CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.
  • Description
    CGP 35348 is a selective antagonist of GABAB receptor (EC50 = 34 μM). CGP 35348 can be used in studies of neuromuscular coordination and spatial learning after neonatal brain damage in albino mice.(In Vivo):In male Wistar rats, CGP 35348(100, 300, and 900 mg/kg) produced an increase in the duration of non-REM sleep and rapid eye movement (REM) sleep and reduced strongly spike-wave discharges.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Eight male Wistar rats Dosage:100, 300, and 900 mg/kg?Administration:Intraperitoneally given Result:Produced an increase in the duration of REM sleep compared to the saline-injected control group at 100 and 300 mg/kg.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    123690-79-9
  • Formula Weight
    225.22
  • Molecular Formula
    C8H20NO4P
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 83.33 mg/mL (369.99 mM)
  • SMILES
    CCOC(OCC)P(CCCN)(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Teófilo TMDS, et al. Phytoextraction of diuron, hexazinone, and sulfometuron-methyl from the soil by green manure species. Chemosphere. 2020 Oct;256:127059.
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