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Picloxydine
CAS No. 5636-92-0
Picloxydine( —— )
Catalog No. M26376 CAS No. 5636-92-0
Picloxydine has antiplaque and antibacterial activity. Picloxydine has a destructive effect on the bacterial cell wall and plasma membrane, which leads to cell lysis and release of intracellular components.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 307 | In Stock |
|
| 10MG | 444 | In Stock |
|
| 25MG | 673 | In Stock |
|
| 50MG | 886 | In Stock |
|
| 100MG | 1209 | In Stock |
|
| 200MG | 1637 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePicloxydine
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NoteResearch use only, not for human use.
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Brief DescriptionPicloxydine has antiplaque and antibacterial activity. Picloxydine has a destructive effect on the bacterial cell wall and plasma membrane, which leads to cell lysis and release of intracellular components.
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DescriptionPicloxydine has antiplaque and antibacterial activity. Picloxydine has a destructive effect on the bacterial cell wall and plasma membrane, which leads to cell lysis and release of intracellular components.(In Vivo):While picloxydine in higher concentration suppressed the oral flora more effectively than chlorhexidine, the latter agent inhibited plaque development to a much greater extent. This lack of correlation between antibacterial and antiplaque activity can be related to structural differences between these two bis-biguanides.
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In Vitro——
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In Vivo0.4% Picloxydine produces a highly significant drop in the number of aerobic organisms. 0.4% Picloxydine is far more effective than 0.2% Picloxydine or chlorhexidine in reducing the total viable count of oral aerobic and anaerobic organisms. Picloxydine is also used in eye drops in the topical therapy of trachoma.
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorCaspase-3| Caspase-9| ERK| MEK1
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Research Area——
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Indication——
Chemical Information
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CAS Number5636-92-0
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Formula Weight475.38
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Molecular FormulaC20H24Cl2N10
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 11.36 mg/mL (23.90 mM)
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SMILESClc1ccc(NC(=N)NC(=N)N2CCN(CC2)C(=N)NC(=N)Nc2ccc(Cl)cc2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lelli D, Pedone C, Sahebkar A. Curcumin and treatment of melanoma: The potential role of microRNAs. Biomed Pharmacother. 2017 Apr;88:832-834.
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