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J8-C8

CAS No. 1150565-77-7

J8-C8( acyl-HSLs inhibitor J8-C8 )

Catalog No. M10530 CAS No. 1150565-77-7

J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

J8-C8
Note

Research use only, not for human use.
Brief Description

J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
Description

J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production; inhibits C8-HSL synthesis in a dose-dependent manner; a new class of quorum sensing (QS)-inhibiting therapeutic agents.
In Vitro

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In Vivo

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Synonyms

acyl-HSLs inhibitor J8-C8
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

1150565-77-7
Formula Weight

237.343
Molecular Formula

C14H23NO2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

N-(3-oxocyclohex-1-en-1-yl)octanamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Chung J, et al. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12089-94.

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