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J8-C8

CAS No. 1150565-77-7

J8-C8( acyl-HSLs inhibitor J8-C8 )

Catalog No. M10530 CAS No. 1150565-77-7

J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    J8-C8
  • Note
    Research use only, not for human use.
  • Brief Description
    J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production.
  • Description
    J8-C8 is a small-molecule inhibitor of bacterial N-acyl-homoserine lactone synthase (acyl-HSLs) TofI with IC50 of 35 uM for toxoflavin production; inhibits C8-HSL synthesis in a dose-dependent manner; a new class of quorum sensing (QS)-inhibiting therapeutic agents.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    acyl-HSLs inhibitor J8-C8
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1150565-77-7
  • Formula Weight
    237.343
  • Molecular Formula
    C14H23NO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    N-(3-oxocyclohex-1-en-1-yl)octanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chung J, et al. Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12089-94.
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