JAK-IN-5( —— )

Catalog No. M26263 CAS No. 2096999-92-5

JAK-IN-5 is a JAK inhibitor (Compound 283 from patent US20170121327A1).

Purity : >98% (HPLC)

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Datasheet

HNMR

HPLC

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Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	567	In Stock
5MG	391	In Stock
10MG	582	In Stock
25MG	928	In Stock
50MG	1228	In Stock
100MG	1655	In Stock
200MG	Get Quote	In Stock
500MG	3311	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

JAK-IN-5
Note

Research use only, not for human use.
Brief Description

JAK-IN-5 is a JAK inhibitor (Compound 283 from patent US20170121327A1).
Description

JAK-IN-5 is a JAK inhibitor (Compound 283 from patent US20170121327A1).
In Vitro

——
In Vivo

JAK-IN-5 (compound 1) (oral aspirate, 0.5 mg/mL, 50 μL ) inhibits STAT6 phosphorylation by 60% in IL-13-induced in lung tissue in a mouse model of pSTAT6 induction.JAK-IN-5 (compound 1) (oral aspirate, 0.1-1.0 mg/mL, 50 μL) inhibits 88% of BALF eosinophils in male C57 mice model of Alternaria alternata-induced eosinophilic inflammation of the lung.
Synonyms

——
Pathway

Angiogenesis
Target

JAK
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

2096999-92-5
Formula Weight

474.584
Molecular Formula

C27H31FN6O
Purity

>98% (HPLC)
Solubility

——
SMILES

CCc1cc(O)c(F)cc1-c1ccc2c(n[nH]c2c1)-c1nc2CN(CCc2[nH]1)C1CCN(C)CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Zhao H, Liu Q et al. In vitro additive antitumor effects of dimethoxycurcumin and 5-fluorouracil in colon cancer cells. Cancer Med. 2017 Jul;6(7):1698-1706.

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