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CYP17-IN-1
CAS No. 2093317-51-0
CYP17-IN-1( —— )
Catalog No. M26134 CAS No. 2093317-51-0
CYP17-IN-1 is an effective oral CYP17 inhibitor that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 249 | In Stock |
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| 2MG | 166 | In Stock |
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| 5MG | 255 | In Stock |
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| 10MG | 374 | In Stock |
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| 25MG | 562 | In Stock |
|
| 50MG | 770 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCYP17-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionCYP17-IN-1 is an effective oral CYP17 inhibitor that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.
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DescriptionCYP17-IN-1 is an effective oral CYP17 inhibitor that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.(In Vitro):The IC50 value of CYP17-IN-1 for CYP3A4 is 8.5 μM.(In Vivo):CYP17-IN-1 dose-dependently reduced plasma testosterone levels in Sprague-Dawley rats.
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In VitroCYP17-IN-1 (compound 9c) exhibits an IC50 value of 8.5 μM against CYP3A4.
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In VivoCYP17-IN-1 (compound 9c) reduces plasma testosterone level in a dose-dependent manner in Sprague-Dawley rats.
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetP450
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Recptorcarbonic anhydrase
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Research Area——
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Indication——
Chemical Information
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CAS Number2093317-51-0
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Formula Weight312.41
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Molecular FormulaC18H17FN2S
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1ccncc1CN1CCc2c(C1)sc1ccc(F)cc21
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Prete SD, et, al. Escherichia coli γ-carbonic anhydrase: characterisation and effects of simple aromatic/heterocyclic sulphonamide inhibitors. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1545-1554.
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