CRAC intermediate 2
CAS No. 123066-64-8
CRAC intermediate 2( —— )
Catalog No. M26130 CAS No. 123066-64-8
CRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 25MG | 49 | In Stock |
|
| 50MG | 77 | In Stock |
|
| 100MG | 116 | In Stock |
|
| 200MG | 170 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCRAC intermediate 2
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NoteResearch use only, not for human use.
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Brief DescriptionCRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis.
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DescriptionCRAC intermediate 2 is a intermediate compound for CRAC inhibitor synthesis. CRAC intermediate 2 has been extracted from patent WO 2013059666A1.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number123066-64-8
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Formula Weight295.188
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Molecular FormulaC11H7F6N3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 52 mg/mL (176.16 mM)
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SMILESNc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Styraxlignolide F
Styraxlignolide F is a natural product from Styrax japonica.
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PKC ζ pseudosubstrat...
Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC ζ-independent pathway.
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Asparagusic acid
Asparagusic acid is unique to asparagus. It is responsible for the odorous urine excreted after eating asparagus. Its derivatives ihydroasparagusic acid have an anti-inflammatory effect.
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