Iberdomide

CAS No. 1323403-33-3

Iberdomide( CC-220 )

Catalog No. M21067 CAS No. 1323403-33-3

Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 91 In Stock
5MG 92 In Stock
10MG 163 In Stock
25MG 326 In Stock
50MG 500 In Stock
100MG 737 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Iberdomide
  • Note
    Research use only, not for human use.
  • Brief Description
    Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
  • Description
    Iberdomide is a modulator of cereblon( IC50 value of 60 nM in a competitive TR-FRET assay).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CC-220
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1323403-33-3
  • Formula Weight
    449.5
  • Molecular Formula
    C25H27N3O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:30 mg/mL (66.74 mM)
  • SMILES
    O=C1CCC(N2Cc3c(OCc4ccc(CN5CCOCC5)cc4)cccc3C2=O)C(=O)N1
  • Chemical Name
    (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-26-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Matyskiela M E Zhang W Man H W et al. A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos[J]. Journal of Medicinal Chemistry 2017:acs.jmedchem.6b01921.
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