Rhodamine 6G

CAS No. 989-38-8

Rhodamine 6G( Basic Red 1 )

Catalog No. M25027 CAS No. 989-38-8

Rhodamine 6G is a rhodamine analog useful in Pgp efflux assays.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 58 In Stock
1G 71 In Stock

Biological Information

  • Product Name
    Rhodamine 6G
  • Note
    Research use only, not for human use.
  • Brief Description
    Rhodamine 6G is a rhodamine analog useful in Pgp efflux assays.
  • Description
    Rhodamine 6G is a rhodamine analog useful in Pgp efflux assays. It can be used in characterizing the kinetics of MRP1- mediated efflux as a laser dye and potential mitochondrial probe. (In Vivo):Melanoma-transplanted mice receiving Rhodamine 6G demonstrate prolonged survival, improved clinical parameters, inhibited tumor growth and metastases count, compared to their untreated counterparts. Twice-a-week 10-6M Rhodamine 6G regimen yield the most prominent results. The Rhodamine-6G enters the circulatory system and labels leukocytes. It is possible to monitor changes in the interactions between leukocytes and the endothelium by determining the numbers of rolling and adhering leukocytes as well as the total flux of these cells.
  • In Vitro
    ——
  • In Vivo
    Melanoma-transplanted mice receiving Rhodamine 6G demonstrate prolonged survival, improved clinical parameters, inhibited tumor growth and metastases count, compared to their untreated counterparts. Twice-a-week 10-6M Rhodamine 6G regimen yield the most prominent results. The Rhodamine-6G enters the circulatory system and labels leukocytes. It is possible to monitor changes in the interactions between leukocytes and the endothelium by determining the numbers of rolling and adhering leukocytes as well as the total flux of these cells.
  • Synonyms
    Basic Red 1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    989-38-8
  • Formula Weight
    479.01
  • Molecular Formula
    C28H31ClN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25 mg/mL (52.19 mM; Need ultrasonic);H2O:< 0.1 mg/mL (insoluble)
  • SMILES
    CC1=CC2=C(C3=CC=CC=C3C(OCC)=O)C4=C([O+]=C2C=C1NCC)C=C(NCC)C(C)=C4.[Cl-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zehentbauer FM, et al. Fluorescence spectroscopy of Rhodamine 6G: concentration and solvent effects. Spectrochim Acta A Mol Biomol Spectrosc. 2014;121:147-51.
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