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BT18
CAS No. 924811-53-0
BT18( —— )
Catalog No. M24975 CAS No. 924811-53-0
BT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 107 | In Stock |
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| 5MG | 76 | In Stock |
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| 10MG | 140 | In Stock |
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| 25MG | 250 | In Stock |
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| 50MG | 370 | In Stock |
|
| 100MG | 547 | In Stock |
|
| 200MG | 792 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBT18
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NoteResearch use only, not for human use.
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Brief DescriptionBT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF).
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DescriptionBT18 is a mimic with function similar to glial cell line-derived neurotrophic factor (GDNF). BT18 has an effect on RET receptor tyrosine kinase RetA and GDNF family receptor GFRα1 function.
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In VitroBT18 (50 μM; 1-90 minutes) activates AKT and ERK1/2 in time-dependently in MG87RET cell lines.BT18 (1-50 μM; 90 minutes) activates AKT in a dose-dependent manner in MG87RET cell lines.BT18 (5-50 μM; 15 mimutes) appears to phosphorylate RET in concentration of 50 μM both in GFP-transfected and in GFRD1-transfected cells. Western Blot Analysis Cell Line:MG87RET cell lines Concentration:50 μM Incubation Time:1, 5, 15, 45, 90 minutes Result:Activated AKT and ERK1/2 in time-dependently.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number924811-53-0
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Formula Weight637.64
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Molecular FormulaC30H31F4N3O6S
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Purity>98% (HPLC)
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SolubilityDMSO: 98 mg/mL (153.69 mM; Need ultrasonic)
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SMILESCOc(ccc(S(N(CC1)Cc(cc2OC)c1cc2OC)(=O)=O)c1)c1N(CC1)CCN1C(c(cc1)c(C(F)(F)F)cc1F)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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