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Penicillic acid

CAS No. 90-65-3

Penicillic acid( —— )

Catalog No. M24943 CAS No. 90-65-3

Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8.Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro.

Purity : >98% (HPLC)

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Biological Information

Product Name

Penicillic acid
Note

Research use only, not for human use.
Brief Description

Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8.Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro.
Description

Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8.Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Microbiology/Virology
Target

Antibiotic
Recptor

Antibiotic|Apoptosis|Bacterial|caspase-8
Research Area

——
Indication

——

Chemical Information

CAS Number

90-65-3
Formula Weight

170.16
Molecular Formula

C8H10O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (587.68 mM)
SMILES

C=C(C)C(/C(OC)=C/C(O)=O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Sorenson WG, et al. Toxicity of penicillic acid for rat alveolar macrophages in vitro. Environ Res. 1986 Dec;41(2):505-13.

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