TG 100572 Hydrochloride( —— )

Catalog No. M24874 CAS No. 867331-64-4

TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

TG 100572 Hydrochloride
Note

Research use only, not for human use.
Brief Description

TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases.
Description

TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 nM for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRβ, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

VEGFR
Recptor

VEGFR1|VEGFR2|FGFR1|FGFR2|PDGFRβ
Research Area

——
Indication

——

Chemical Information

CAS Number

867331-64-4
Formula Weight

512.43
Molecular Formula

C26H27Cl2N5O2
Purity

>98% (HPLC)
Solubility

DMSO : 20 mg/mL?(39.03 mM;?Need ultrasonic)
SMILES

ClC1=CC=C(O)C=C1C2=CC(C)=C(N=C(NC(C=C3)=CC=C3OCCN4CCCC4)N=N5)C5=C2.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Doukas J, et al. Topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema. J Cell Physiol. 2008 Jul;216(1):29-37.

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