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Andrograpanin
CAS No. 82209-74-3
Andrograpanin( 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE )
Catalog No. M24811 CAS No. 82209-74-3
Andrograpanin is a bioactive compound from Andrographis paniculata.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 139 | In Stock |
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| 5MG | 132 | In Stock |
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| 10MG | 188 | In Stock |
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| 25MG | 313 | In Stock |
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| 50MG | 458 | In Stock |
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| 100MG | 667 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAndrograpanin
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NoteResearch use only, not for human use.
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Brief DescriptionAndrograpanin is a bioactive compound from Andrographis paniculata.
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DescriptionAndrograpanin is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
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In VitroAndrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways.Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells.
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In Vivo——
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Synonyms19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE
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PathwayMAPK/ERK Signaling
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Targetp38 MAPK
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Recptorp38 MAPK
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Research Area——
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Indication——
Chemical Information
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CAS Number82209-74-3
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Formula Weight318.45
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Molecular FormulaC20H30O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (314.02 mM)
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SMILESC[C@@](CO)(CCC1)[C@@H](CC2)[C@]1(C)[C@H](CCC1=CCOC1=O)C2=C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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p38-α MAPK-IN-1
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.
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Bisabolangelone
Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.Bisabolangelone (BISA), isolated from the roots of Angelica koreana, has many pharmacological activities, such as anti-tumor, anti-microbial, antioxidant, and anti-inflammatory activities.?
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HS-276
HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM). HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used to study rheumatoid arthritis (RA).
