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Andrograpanin

CAS No. 82209-74-3

Andrograpanin( 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE )

Catalog No. M24811 CAS No. 82209-74-3

Andrograpanin is a bioactive compound from Andrographis paniculata.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Andrograpanin
  • Note
    Research use only, not for human use.
  • Brief Description
    Andrograpanin is a bioactive compound from Andrographis paniculata.
  • Description
    Andrograpanin is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
  • In Vitro
    Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways.Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells.
  • In Vivo
    ——
  • Synonyms
    19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    p38 MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    82209-74-3
  • Formula Weight
    318.45
  • Molecular Formula
    C20H30O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (314.02 mM)
  • SMILES
    C[C@@](CO)(CCC1)[C@@H](CC2)[C@]1(C)[C@H](CCC1=CCOC1=O)C2=C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu J , Wang Z T , Ge B X . Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways[J]. International Immunopharmacology, 2008, 8(7):951-958.
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