Andrograpanin

CAS No. 82209-74-3

Andrograpanin( 19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE )

Catalog No. M24811 CAS No. 82209-74-3

Andrograpanin is a bioactive compound from Andrographis paniculata.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 139 In Stock
5MG 132 In Stock
10MG 188 In Stock
25MG 313 In Stock
50MG 458 In Stock
100MG 667 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Andrograpanin
  • Note
    Research use only, not for human use.
  • Brief Description
    Andrograpanin is a bioactive compound from Andrographis paniculata.
  • Description
    Andrograpanin is a bioactive compound from Andrographis paniculata. Andrograpanin has anti-inflammatory and anti-infectious properties.
  • In Vitro
    Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways.Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells.
  • In Vivo
    ——
  • Synonyms
    19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    p38 MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    82209-74-3
  • Formula Weight
    318.45
  • Molecular Formula
    C20H30O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (314.02 mM)
  • SMILES
    C[C@@](CO)(CCC1)[C@@H](CC2)[C@]1(C)[C@H](CCC1=CCOC1=O)C2=C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu J , Wang Z T , Ge B X . Andrograpanin, isolated from Andrographis paniculata, exhibits anti-inflammatory property in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways[J]. International Immunopharmacology, 2008, 8(7):951-958.
molnova catalog
related products
  • VX-702

    A potent, selective, second generation p38 MAPK inhibitor with IC50 of 4-20 nM for p38α.

  • BMS-751324

    BMS-751324 is a novel clinical prodrug of BMS-582949, which is a highly selective p38α MAPK inhibitor with IC50 of 13 nM.

  • Bisabolangelone

    Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling.Bisabolangelone (BISA), isolated from the roots of Angelica koreana, has many pharmacological activities, such as anti-tumor, anti-microbial, antioxidant, and anti-inflammatory activities.?