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Tocainide hydrochloride

CAS No. 71395-14-7

Tocainide hydrochloride ( 2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride )

Catalog No. M24724 CAS No. 71395-14-7

Tocainide hydrochloride is a sodium channel blocker. It blocks the sodium channels in the pain-producing foci in the nerve membranes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tocainide hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Tocainide hydrochloride is a sodium channel blocker. It blocks the sodium channels in the pain-producing foci in the nerve membranes.
  • Description
    Tocainide hydrochloride is a sodium channel blocker. It blocks the sodium channels in the pain-producing foci in the nerve membranes.
  • In Vitro
    ——
  • In Vivo
    Tocainide (100 mg/kg) effectively suppresses ventricular ectopic activity in unanesthetized dogswith coronary occlusion. Termination of tocainide infusion in both digitalis toxicity and coronary occlusion models results in prompt return of ventricular ectopic activity.
  • Synonyms
    2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    71395-14-7
  • Formula Weight
    228.72
  • Molecular Formula
    C11H17ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (546.52 mM)
  • SMILES
    Cl.CC(N)C(=O)Nc1c(C)cccc1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Alpert JS, et al. Chemistry, pharmacology, antiarrhythmic efficacy and adverse effects of tocainide hydrochloride, an orally active structural analog of lidocaine. Pharmacotherapy. 1983 Nov-Dec;3(6):316-23.
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