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Endoxifen HCl
CAS No. 1032008-74-4
Endoxifen HCl( Z-Endoxifen HCl | Z Endoxifen HCl | ZEndoxifen Hydrochloride )
Catalog No. M17762 CAS No. 1032008-74-4
Endoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 96 | In Stock |
|
| 50MG | 314 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameEndoxifen HCl
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NoteResearch use only, not for human use.
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Brief DescriptionEndoxifen HCl is the active metabolite of Tamoxifen, which is an effective and selective estrogen receptor antagonist.
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DescriptionZ-Endoxifen HCl is an estrogen receptor alpha (ERalpha) ligand, potent antiestrogen, and metabolite of tamoxifen. Z-endoxifen is the most potent of the metabolites of tamoxifen, and has the potential to be more effective than tamoxifen because it bypasses potential drug resistance mechanisms attributable to patient variability in the expression of the hepatic microsomal enzyme CYP2D6.
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In Vitro——
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In Vivo——
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SynonymsZ-Endoxifen HCl | Z Endoxifen HCl | ZEndoxifen Hydrochloride
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorER
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1032008-74-4
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Formula Weight409.95
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Molecular FormulaC25H28ClNO2
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Purity>98% (HPLC)
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SolubilityDMSO : 12.5 mg/mL 30.49 mM; H2O : < 0.1 mg/mL
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SMILESCC/C(=C(\c1ccc(cc1)O)/c1ccc(cc1)OCCNC)/c1ccccc1.Cl
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Chemical Name4-[(Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chae YJ, et al. Endoxifen, the active metabolite of tamoxifen, inhibits cloned hERG potassium channels. Eur J Pharmacol. 2015 Apr 5;752:1-7.
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