D-Glutamic acid( (R)-Glutamic acid )

Catalog No. M24704 CAS No. 6893-26-1

D-glutamic acid, the enantiomer of L-glutamic acid, is widely used in medicine and food.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

D-Glutamic acid
Note

Research use only, not for human use.
Brief Description

D-glutamic acid, the enantiomer of L-glutamic acid, is widely used in medicine and food.
Description

D-glutamic acid, the enantiomer of L-glutamic acid, is widely used in medicine and food.
In Vitro

Various d-amino acids, such as D-serine, D-aspartic acid (D-Asp), and D-glutamic acid (D-Glu) are widely found in mammals including human beings and they are now thought to be the candidates of novel physiologically active substances and/or biomarkers. D-[Asp/Glu] (4 mg/mL) inhibits IgE binding (75%) to peanuts while D-Glu, D-Asp has no inhibitory effect. IgE is specific for D-[Asp/Glu] and may have the potential for removing IgE or reducing IgE binding to peanut allergens.
In Vivo

D-glutamic acid is currently paid attention as a modulator of neuronal transmission and hormonal secretion. It is metabolized only by D-aspartate oxidase in mammals. After intraperitoneal injection, L-glutamate is catabolized via a-ketoglutarate, whereas D-glutamate is converted to n-pyrrolidone carboxylic acid. Carbon 2 of both D- and L-glutamate is converted in the cecum to the methyl carbon of acetate. Both rat liver and kidney catalyze the conversion of D-glutamic acid to n-pyrrolidone carboxylic acid.
Synonyms

(R)-Glutamic acid
Pathway

Proteasome/Ubiquitin
Target

Endogenous Metabolite
Recptor

Human Endogenous Metabolite
Research Area

——
Indication

——

Chemical Information

CAS Number

6893-26-1
Formula Weight

147.13
Molecular Formula

C5H9NO4
Purity

>98% (HPLC)
Solubility

H2O:10 mg/mL (67.97 mM; Need ultrasonic)
SMILES

N[C@H](CCC(O)=O)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Han H, et al. Changes in D-aspartic acid and D-glutamic acid levels in the tissues and physiological fluids of mice with various D-aspartate oxidase activities. J Pharm Biomed Anal. 2015 Dec 10;116:47-52.

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