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Benzonitrile, 3,3-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)
Benzonitrile, 3,3-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)
CAS No. 63476-70-0
Benzonitrile, 3,3-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)( —— )
Catalog No. M24644 CAS No. 63476-70-0
Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μM
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 164 | In Stock |
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| 10MG | 241 | In Stock |
|
| 25MG | 411 | In Stock |
|
| 50MG | 590 | In Stock |
|
| 100MG | 827 | In Stock |
|
| 500MG | 1647 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameBenzonitrile, 3,3-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)
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NoteResearch use only, not for human use.
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Brief DescriptionBenzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μM
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DescriptionBenzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μM
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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Targetp53
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Recptorp53
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Research Area——
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Indication——
Chemical Information
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CAS Number63476-70-0
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Formula Weight324.38
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Molecular FormulaC22H16N2O
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(/C(CCC/1)=C/C2=CC(C#N)=CC=C2)C1=C\C3=CC=CC(C#N)=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Rezatapopt
Rezatapopt (PC14586) is a small molecule p53 reactivator with anti-tumor activity that selectively binds to the cleft present in the TP53 Y220C mutant protein and restores the p53 wild-type (normal) conformation and transcriptional activity, and can be used to study locally advanced or metastatic solid tumors.
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Amifostine thiol dih...
WR-1065 dihydrochloride can activate p53 through a JNK-dependent signaling pathway. It also protects normal tissues from the toxic effects of certain cancer drugs.
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Rotenone
Rotenone is an odorless, colorless, crystalline ketonic chemical compound used as a broad-spectrum insecticide, piscicide, and pesticide.
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