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Ergolide
CAS No. 54999-07-4
Ergolide( —— )
Catalog No. M24538 CAS No. 54999-07-4
Ergolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 169 | In Stock |
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| 5MG | 142 | In Stock |
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| 10MG | 242 | In Stock |
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| 25MG | 394 | In Stock |
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| 50MG | 537 | In Stock |
|
| 100MG | 720 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameErgolide
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NoteResearch use only, not for human use.
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Brief DescriptionErgolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB.
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DescriptionErgolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB. Ergolide is a sesquiterpene lactone isolated from the dried flowers of Inula Britannica.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB
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Research Area——
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Indication——
Chemical Information
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CAS Number54999-07-4
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Formula Weight306.35
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Molecular FormulaC17H22O5
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (163.21 mM; Need ultrasonic)
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SMILESC[C@H](C[C@@H]([C@H]([C@@H]1OC(C)=O)C2=C)OC2=O)[C@H](CC2)[C@@]1(C)C2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Urolithin B
Urolithin B inhibits NF-κB activity by reducing the phosphorylation and degradation of IκBα, and suppresses the phosphorylation of JNK, ERK, and Akt, and enhances the phosphorylation of AMPK.?Urolithin B is also a regulator of skeletal muscle mass.Urolithin B is one of the gut microbial metabolites of ellagitannins, and has anti-inflammatory and antioxidant effects.
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BML-190
BML-190 is a specific CB2 receptor inverse agonist (Ki: 435 nM), with 50-fold selectivity over CB1 receptor.
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NF-κΒ activator 2
NF-κΒ activator 2 is a potent and orally active NF-κB activator, with an EC 50 of 1.58 μM. NF-κΒ activator 2 induces SOD 2 through increasing NF-κB expression and activation. NF-κΒ activator 2 can be used for the research of amyotrophic lateral sclerosis (ALS) .
